Home > Subtypes of CAPS > FCAS Facts > FCAS Symptoms


Discuss Your Discomfort: Onset of FCAS Symptoms

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People with Familial Cold Autoinflammatory Syndrome (FCAS) usually start having symptoms at birth. Occasionally, symptoms may start later in childhood.

Symptoms of FCAS disorder, the most common subtype of Cryopyrin-Associated Periodic Syndromes (CAPS), begin after a person is exposed to cold temperatures. For example, being in an air-conditioned room can bring on symptoms. A rash will usually start 1 to 2 hours after exposure to the cold, followed by other symptoms 4 to 6 hours later.

Duration of FCAS symptoms

There may be days when some FCAS symptoms are not felt. Symptoms can develop at any time of the day and may progress into the evening. While some symptoms can last longer, FCAS symptoms usually last no more than 24 hours.